Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reissue Patent
2006-08-15
2006-08-15
Bugaisky, Gabriele (Department: 1656)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S324000, C530S326000, C530S325000, C514S013800, C514S014800
Reissue Patent
active
RE039240
ABSTRACT:
Substantially pure conotoxins are provided which inhibit synaptic transmissions at the neuromuscular junctions and which are useful both in vivo and in assays because they specifically target particular receptors, such as the acetyl-choline receptor, and ion channels. The peptides are of such length that they can be made by chemical synthesis. They also may be made using recombinant DNA techniques, and the DNA encoding such conotoxins having pesticidal properties can be incorporated as plant defense genes into plant species of interest.
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Abogadie Fe
Cruz Lourdes J.
Dykert John
Hopkins Chris E.
Olivera Baldomero M.
Bugaisky Gabriele
Rothwell Figg Ernst & Manbeck
The Salk Institute for Biological Studies
University of Utah Research Foundation
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