Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1995-06-02
1997-12-23
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530324, 530326, 530325, 514 13, 514 14, C07K 708
Patent
active
057007780
ABSTRACT:
Substantially pure conotoxins are provided which inhibit synaptic transmissions at the neuromuscular junctions and which are useful both in vivo and in assays because they specifically target particular receptors, such as the acetylcholine receptor, and ion channels. The peptides are of such length that they can be made by chemical synthesis. They also may be made using recombinant DNA techniques, and the DNA encoding such conotoxins having pesticidal properties can be incorporated as plant defense genes into plant species of interest.
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Abogadie Fe
Cruz Lourdes J.
Dykert John
Hopkins Chris E.
Olivera Baldomero M.
Delaney Patrick R.
The Salk Institute for Biological Studies
Tsang Cecilia J.
University of Utah Research Foundation
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