Connective tissue regeneration using human mesenchymal stem cell

Details Connective tissue regeneration using human mesenchymal stem cell Connective tissue regeneration using human mesenchymal stem cell

1995-04-11

1998-09-22

Lankford, Jr., Leon B.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Animal or plant cell

435366, 435372, C12N 500, C11N 502

Patent

active

058110941

ABSTRACT:
Isolated human mesenchymal stem cells, a method for isolating, purifying, and culturally expanding human mesenchymal stem cells (i.e. mesenchymal stem cells or "MSCs"), and characterization of (including by cytokine expression profiling) and uses, particularly research reagent, diagnostic and therapeutic uses for such cells. The stem cells can be culture expanded without differentiating. Monoclonal antibodies specific for human mesenchymal stem cells and the monoclonal hybridoma cell lines (ATCC nos. 10743-10745) that synthesize and secrete these monospecific antibodies, and uses of the monoclonal antibodies for diagnostic and/or therapeutic purposes.

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