Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Hormones – e.g. – prolactin – thymosin – growth factors – etc.
Patent
1993-12-14
1995-04-18
Draper, Garnette D.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Hormones, e.g., prolactin, thymosin, growth factors, etc.
5303879, 435 694, 930120, A61K 3736, C07K 1300
Patent
active
054080401
ABSTRACT:
A novel chemotactic and mitogenic protein, Connective Tissue Growth Factor (CTGF), a polynucleotide that encodes CTGF and antibodies that bind to CTGF are provided. Diagnostic and therapeutic methods using CTGF are also described.
REFERENCES:
Shimokado et al. Cell 43:277-286 Nov. 1985.
Campochiaro et al. Exp. Eye. Res 49:217-227, 1989.
Matsuoka et al. Proc. Nat. Acad. Sci 86:4416-4420 Jun. 1989.
Ryseck, R-P. et al. Cell Growth & Differentiation 2:225-233 May 1991.
Bradham, Jr. Douglas M.
Grotendorst Gary R.
Draper Garnette D.
Spector Lorraine M.
University of South Florida
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