Conjugation reactions

Details Conjugation reactions Conjugation reactions

2004-01-16

2011-11-08

Eashoo, Mark (Department: 1767)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

Reexamination Certificate

active

08053520

ABSTRACT:
An initiator for the terminal group of the polymer product of an atom or group radical transfer polymerisation has an activated carboxyl or an amine group which is reacted with an amine or carboxyl (respectively) group containing biologically active compound. The initiator is preferably 4-(3-(2-bromo, 2-methyl-propionate)phenyl)-propionic acid N-hydroxysuccinimide ester or 2-bromo, 2-methyl-propionic acid N-hydroxysuccinimide ester. The monomers preferably comprise a zwitterionic monomer such as 2-methacryloxyethyl-2′-trimethyl ammoniumethyl phosphate inner salt.

REFERENCES:
patent: 5122614 (1992-06-01), Zalipsky
patent: 5191015 (1993-03-01), Sheppard et al.
patent: 5198493 (1993-03-01), Holmberg et al.
patent: 5260373 (1993-11-01), Profy et al.
patent: 5328955 (1994-07-01), Rhee et al.
patent: 5444150 (1995-08-01), Inman et al.
patent: 5658561 (1997-08-01), Nakabayashi et al.
patent: 5807937 (1998-09-01), Matyjaszewski et al.
patent: 5855987 (1999-01-01), Margel et al.
patent: 5888990 (1999-03-01), Chasalow
patent: 5932462 (1999-08-01), Harris et al.
patent: 6113906 (2000-09-01), Greenwald et al.
patent: 6127349 (2000-10-01), Chasalow
patent: 6251382 (2001-06-01), Greenwald et al.
patent: 6310149 (2001-10-01), Haddleton
patent: 6562330 (2003-05-01), Stratford et al.
patent: 6803438 (2004-10-01), Brocchini et al.
patent: 6828029 (2004-12-01), Lewis et al.
patent: 6833276 (2004-12-01), Klaerner et al.
patent: 6852816 (2005-02-01), Lewis et al.
patent: 7300990 (2007-11-01), Lewis et al.
patent: 7365127 (2008-04-01), Wu et al.
patent: 2002/0141965 (2002-10-01), Ahn et al.
patent: 2003/0158333 (2003-08-01), Roberts et al.
patent: 2004/0029794 (2004-02-01), Veronese et al.
patent: 2004/0030101 (2004-02-01), Bailon et al.
patent: 2004/0091451 (2004-05-01), Charreyre et al.
patent: 2004/0157276 (2004-08-01), Sumida et al.
patent: 2004/0162388 (2004-08-01), Tjoeng
patent: 2004/0235734 (2004-11-01), Bossard et al.
patent: 2005/0112203 (2005-05-01), Shau et al.
patent: 2005/0123501 (2005-06-01), Lewis
patent: 2005/0163743 (2005-07-01), Lewis
patent: 2005/0220880 (2005-10-01), Lewis
patent: 2006/0069203 (2006-03-01), Lewis
patent: 2007/0123646 (2007-05-01), Lele et al.
patent: 2007/0276088 (2007-11-01), Maynard et al.
patent: 2008/0206182 (2008-08-01), Sommermeyer et al.
patent: 2010/0166700 (2010-07-01), Charles
patent: 2000093169 (2000-04-01), None
patent: WO 93/01221 (1993-01-01), None
patent: 93/15775 (1993-08-01), None
patent: WO 96/30421 (1996-10-01), None
patent: 98/43676 (1998-10-01), None
patent: 01/27209 (2001-04-01), None
patent: WO 02/28929 (2002-04-01), None
patent: WO 02/100439 (2002-12-01), None
patent: WO 03/062290 (2003-07-01), None
patent: WO 03/074026 (2003-09-01), None
patent: WO 03/074090 (2003-09-01), None
patent: WO 03/074090 (2003-09-01), None
Monfardini et al. (Bioconjuate Chem. 1995, 6, 62-69).
Chen et al. J. Biomater. Sci. Polymer Edn. vol. 5(4), p. 371-382, 1994.
Machine Translation of JP 2000-093169 A, 2010.
E.J. Ashford et al., “First example of the atom transfer radical polymerization of an acidic monomer: direct synthesis of methacrylic acid copolymers in aqueous media”,Chem. Commun.,, XP-002276944, 1999, pp. 1285-1286.
Chen et al, “Controlled/‘living’ radical polymerization of MMA via in situ ATRP process”, Chem. Commun., 2000, pp. 233-234.

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