Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Mixing of two or more solid polymers; mixing of solid...
Patent
1988-01-20
1989-07-11
Kight, John
Synthetic resins or natural rubbers -- part of the class 520 ser
Synthetic resins
Mixing of two or more solid polymers; mixing of solid...
530351, 514 12, C08L 8900, C07G 700, A61K 3702
Patent
active
048473251
ABSTRACT:
A biologically active CSF-1 protein is selectively conjugated via certain amino acid residues or carbohydrate moieties to a water-soluble polymer selected from polyethylene glycol or polypropylene glycol homopolymers, polyoxyethylated polyols, or polyvinyl alcohol. The resulting conjugated CSF-1 is biologically active and has increased circulating half-life in mammals, compared to that of the unconjugated protein. The conjugated CSF-1 may be used to stimulate the immune response or to provide more cells to be stimulated.
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Katre Nandini
Koths Kirston E.
Moreland Margaret
Shadle Paula J.
Cetus Corporation
Halluin Albert P.
Kight John
Nutter Nathan M.
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