Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Patent
1995-11-06
1998-10-06
Ceperley, Mary E.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
436526, 436529, 436530, 436533, 530807, 530811, 530814, 530815, G01N 33546, G01N 33552, G01N 33553
Patent
active
058175270
ABSTRACT:
A new method for immobilization of small molecules on solid supports via a macromolecular spacer has been developed. A protein or another macromolecule is first immobilized in an aqueous medium, and the solid support is than washed with an organic solvent. The small molecule is coupled in an organic medium, followed by organic medium washes. The new solid phases are useful for affinity purifications, immunoassays and other binding assays, and for selection of binders by panning procedures.
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Chang Steve C. S.
Peterson James W.
Piran Uri
Riordan William J.
Sunshine Edward M.
Blackburn Robert P.
Ceperley Mary E.
Chiron Diagnostics Corporation
Morgenstern Arthur S.
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