Conjugates useful in the treatment of prostate cancer

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 8, 514 16, 514 17, 514 18, 514 34, 514283, 530300, 530322, 530328, 530329, 530330, 530345, 536 64, 540478, A61K 3808, A61K 3814, C07K 706, C07K 900

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active

059487500

ABSTRACT:
Chemical conjugates which comprise oligopeptides, having amino acid sequences that are selectively proteolytically cleaved by free prostate specific antigen (PSA) and known cytotoxic agents are disclosed. Such conjugates are useful in the treatment of prostatic cancer and benign prostatic hypertrophy (BPH).

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