Conjugates possessing ortho ligating functionality and complexes

Details Conjugates possessing ortho ligating functionality and complexes Conjugates possessing ortho ligating functionality and complexes

1995-06-06

1997-12-09

Kight, John

Organic compounds -- part of the class 532-570 series

Organic compounds

Radioactive metal containing

534 16, 5303915, C07F 300, C07F 500, A61K 4300, A61K 4902

Patent

active

056962398

ABSTRACT:
A group of functionalized amine chelants having ortho ligating functionality that form complexes with rare-earth type metal ions are disclosed. The complexes can be covalently attached to an antibody or antibody fragment and used for therapeutic and/or diagnostic purposes. In addition certain of the chelant-radionuclide complexes can be effectively employed in compositions useful as therapeutic and/or diagnostic agents for calcific tumors and/or relief of bone pain.

REFERENCES:
patent: 2763680 (1956-09-01), Sallmann
patent: 3825592 (1974-07-01), McCrary et al.
patent: 4316883 (1982-02-01), de Schrijver
patent: 4418208 (1983-11-01), Nunn et al.
patent: 4714607 (1987-12-01), Klaveness
patent: 4801722 (1989-01-01), Hinshaw et al.
patent: 4925651 (1990-05-01), Coenen et al.
patent: 5006643 (1991-04-01), Fazio et al.
patent: 5010191 (1991-04-01), Engelstad et al.
patent: 5342604 (1994-08-01), Wilson et al.

Affiliated with

Also associated with

Rating

Conjugates possessing ortho ligating functionality and complexes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Conjugates possessing ortho ligating functionality and complexes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Conjugates possessing ortho ligating functionality and complexes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1608922