Conjugates of superoxide dismutase coupled to high molecular wei

Details Conjugates of superoxide dismutase coupled to high molecular wei Conjugates of superoxide dismutase coupled to high molecular wei

1989-07-13

1991-04-09

Kulkosky, Peter F.

Drug, bio-affecting and body treating compositions

Solid synthetic organic polymer as designated organic active...

Polymer from ethylenic monomers only

424 941, 435180, 435181, A61K 3174, A61K 3748

Patent

active

050063332

ABSTRACT:
A biologically persistent, water-soluble, substantially non-immunogenic, substantially non-antigenic conjugate of superoxide dismutase is prepared by coupling one to five strands of a polyalkylene glycol which is polyethylene glycol or polyethylene-polypropylene glycol copolymer, wherein said polyalkylene glycol has an average molecular weight of about 35,000-1,000,000.

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