Conjugates of defined stoichiometry

Details Conjugates of defined stoichiometry Conjugates of defined stoichiometry

2011-03-01

2011-03-01

Yu, Melanie J. (Department: 1641)

Chemistry: analytical and immunological testing

Including chromatography

C073S061520, C210S656000, C435S007100, C435S961000, C435S962000, C436S544000

Reexamination Certificate

active

07897404

ABSTRACT:
The invention relates to a process for the production of a biomolecule-linker conjugate of uniform stochiometry. It especially relates to a conjugate consisting of a biomolecule of a molecular weight between 5 kD and 500 kD and a hydrophilic linker molecule said linker having a molecular weight between 1 and 15 kD and between 4 and 60 charged residues, characterized in that said conjugate comprises at least one biomolecule-linker product of uniform stoichiometry in a pre-selected amount.

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