Conjugates of apotransferrin proteins with anti-tumor agents

Details Conjugates of apotransferrin proteins with anti-tumor agents Conjugates of apotransferrin proteins with anti-tumor agents

1988-07-12

1989-12-12

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424101, 514 21, 530380, 530389, 530391, 530406, 530410, 530807, 530828, 530394, 530392, 436529, A61K 3714, A61K 39385, A61K 3702, C07K 1514

Patent

active

048867802

ABSTRACT:
Conjugates of transferrin or ceruloplasmin with anti-tumor agents. Such conjugates are useful in the treatment of tumors. Suitable anti-tumor agents include adriamycin, daunomycin, methotrexate, vincristin, 6-mercaptopurine, cytosine arabinoside and cyclophosphamide. Transferrin or ceruloplasmin is preferably coupled to the anti-tumor agent by means of glutaraldehyde.

REFERENCES:
patent: 3939258 (1976-02-01), Niemann
patent: 4046722 (1977-09-01), Rowland
patent: 4174384 (1979-11-01), Ullman et al.
patent: 4256632 (1981-03-01), Levin et al.
patent: 4320109 (1982-03-01), Nakamura et al.
patent: 4332785 (1982-05-01), Allen et al.
patent: 4376765 (1983-03-01), Trouet et al.
patent: 4378428 (1983-03-01), Farina et al.
patent: 4434156 (1984-02-01), Trowbridge
patent: 4447547 (1984-05-01), Allen et al.
patent: 4448762 (1984-05-01), Richards et al.
patent: 4448763 (1984-05-01), Triplett
patent: 4460561 (1984-07-01), Goldenberg
patent: 4493793 (1985-01-01), Chu
patent: 4522750 (1985-06-01), Ades et al.
patent: 4590001 (1986-05-01), Stjernholm
The Lancet, Aug. 23, 1980, Faulk et al, 390-392.
Makromol. Chem. Suppl. 207-214 (1979), Wilchek.
Nature, 294 (1981), 171-173, Trowbridge et al.

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