Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – In an organic compound
Reexamination Certificate
2007-01-09
2007-01-09
Hartley, Michael G. (Department: 1618)
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
In an organic compound
C424S009100, C424S009300
Reexamination Certificate
active
10399265
ABSTRACT:
The invention provides radiopharmaceuticals for diagnostic and therapeutic applications, conjugates of antioxidants with metal chelating ligands, intermediate compounds, methods of making such radiopharmaceuticals, ligands, and intermediate compounds, and kits for preparing the radiopharmaceutical complexes.
REFERENCES:
Beaupere, D. et al; “Selective Azidation of L Sorbose Application to the Rapid Synthesis of 1 Deoxynojirmycin”,Carbohydrate Research, vol. 191, No. 1, pp. 163-166, 1989.
Lewis, M et al.; “Maleimidocysteineamido-DOTA derivatives: New Reagents for Radiometal Chelate Conjugation to Antibody Sulfhydryl Groups”,Bioconjugate Chemisty, vol. 9, No. 1, Jan. 1998.
Ranganathan, R. et al.; “Synthesis of Conjugates of Ascorbic Acid with Metal Chelates”,Abstracts of Papers American Chemical Society, vol. 221, No. 1-2, p. Carb 59, 2001.
PCT Search Report for PCT/US01/46002 mailed Jun. 11, 2003.
Fan Helen
Ranganathan Ramachandran S.
Tweedle Michael F.
Bracco International BV
Hartley Michael G.
Kramer Levin Naftalis & Frankel LLP
Perreira Melissa
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