Conjugates of anticoagulant and protein

Details Conjugates of anticoagulant and protein Conjugates of anticoagulant and protein

1985-03-26

1987-01-06

Kight, John

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

530362, 530363, 530382, 530386, 514 2, 514 56, 514802, 514822, 536 21, 424101, C08B 3710

Patent

active

046347623

ABSTRACT:
Conjugates are provided which are covalently bonded conjugates of an anticoagulant and protein that are prepared in the presence of a coupling agent that forms amide linkages between the anticoagulant and the protein. Such amide linking coupling agents exclude highly toxic coupling agents such as CNBr. These conjugates are useful for enhancing the blood compatibility of certain surfaces of a prosthetic device, a surgical apparatus, or an extra-corporeal medical device.

REFERENCES:
patent: 3099600 (1963-07-01), Toccaceli
patent: 4001200 (1977-01-01), Bonsen et al.
patent: 4003792 (1977-01-01), Mill et al.
patent: 4082507 (1978-04-01), Sawyer
patent: 4110432 (1978-08-01), Wilkinson et al.
patent: 4326532 (1982-04-01), Hammar
patent: 4329383 (1982-05-01), Joh
patent: 4342739 (1982-08-01), Kakimi et al.
Article, Chemical Abstracts, vol. 77, No. 17003r, p. 296, Jul. 1972, Yunosov, R.V.
Article, Thrombosis Research, vol. 7, 1975, pp. 273-284, Teien et al.

Affiliated with

Also associated with

Rating

Conjugates of anticoagulant and protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Conjugates of anticoagulant and protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Conjugates of anticoagulant and protein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-684732