Conjugates formed by reacting a prostaglandin mimic compound wit

Details Conjugates formed by reacting a prostaglandin mimic compound wit Conjugates formed by reacting a prostaglandin mimic compound wit

1977-09-21

1980-03-11

Danison, Walter C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112R, 2601125R, 424 85, A61K 3702, A61K 3900

Patent

active

041927990

ABSTRACT:
A method for the radioimmunoassay of PGE.sub.1 -type and PGE.sub.2 -type compounds and PGX is disclosed which utilizes antibodies formed against a prostaglandin mimic.
Conjugates are disclosed which are formed by attaching a prostaglandin mimic to a carrier molecule.
Antibodies are disclosed which are specific against PGE.sub.1 -type and PGE.sub.2 -type compounds, PGH.sub.2, and PGX.
Complexes are disclosed which are formed by binding an antibody raised against a prostaglandin mimic with its corresponding authentic prostaglandin.

REFERENCES:
patent: 3867366 (1975-02-01), Rubenstein et al.
patent: 3950363 (1976-04-01), Bundy
patent: 3980764 (1976-09-01), Adams
patent: 4041076 (1977-08-01), Arenia et al.
patent: 4053459 (1977-10-01), Christenson
Corey et al, Proc. Nat. Acad. Sci., vol. 72, No. 9, Sept. (1975), pp. 3355-3358.
Corey et al, J.A.C.S., vol. 99, No. 6 (Mar. 1977), pp. 2006-2008.

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