Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing alpha or beta amino acid or substituted amino acid...
Reexamination Certificate
2011-08-02
2011-08-02
Kosar, Andrew D (Department: 1654)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing alpha or beta amino acid or substituted amino acid...
C514S045000, C514S049000, C435S007230
Reexamination Certificate
active
07989188
ABSTRACT:
The present invention relates to conjugates of a drug and an amino acid or an amino acid derivative or analog, pharmaceutical compositions that include the conjugates and methods of use thereof. In particular, the present invention relates to conjugates of anti-proliferative drugs and asparagine and glutamine and analogs thereof as compositions for treatment of cancer, and conjugates of imaging agent carriers and amino acids for the diagnosis of tumors and metastases.
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Gengrinovitch Stela
Izakovich Esther
BioSight Ltd.
Gudibande Satyanarayana R
Kosar Andrew D
Winston & Strawn LLP
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