Conjugated polymer tag complexes

Details Conjugated polymer tag complexes Conjugated polymer tag complexes

2000-10-07

2011-11-01

Cook, Lisa (Department: 1641)

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

C435S007100, C435S007210, C436S518000, C422S050000, C424S009322, C424S078080

Reexamination Certificate

active

08048659

ABSTRACT:
A tagged water-soluble polymer linked to a solid support is provided and includes a solid support optionally including a spacer sequence including one or more spacer monomer units attached to the solid support; and a water-soluble polymer covalently linked to the solid support or to the spacer sequence, the water-soluble polymer including a first cleavage segment including at least one monomer unit including a selectively cleavable link to the solid support or to the spacer sequence, where cleavage of the selectively cleavable link separates the water-soluble polymer from the solid support, a second segment including at least one monomer unit selected from a monomer unit linked to a reactive functionality able to be covalently coupled to a tag or linked to a tag, a third segment including one or more monomer units linked to a reactive functionality that can form a covalent bond with an analyte-binding species or an analyte, and optionally one or more spacer monomer units provided adjacent to any segment and/or between any two segments and/or within any one or more of the second segment and the third segment.

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