Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Reexamination Certificate
2005-06-21
2005-06-21
Henley, III, Raymond J. (Department: 1614)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
Reexamination Certificate
active
06908946
ABSTRACT:
The present invention provides a method of using conjugated nonadecadienoic acid (CNA), one of its derivatives, or a combination thereof to inhibit lipoprotein lipase activity associated with a cell, to control body fat in a human or non-human animal, to inhibit cyclooxygenase activity in a cell, to inhibit platelet aggregation in a human or non-human animal, and to prevent or treat a condition or disease related to platelet aggregation.
REFERENCES:
patent: 5855917 (1999-01-01), Cook et al.
patent: 6060304 (2000-05-01), Pariza et al.
patent: 6126960 (2000-10-01), Nilsen et al.
patent: 6184009 (2001-02-01), Cain et al.
patent: 6316645 (2001-11-01), Sih et al.
patent: 6555579 (2003-04-01), Kritchevsky
patent: 2003/0091654 (2003-05-01), Katz et al.
patent: WO 98/09621 (1998-03-01), None
patent: WO 01/17526 (2001-03-01), None
Park et al. Lipids, vol. 32, No. 8 (1997) pp853-858.
Carballeira NM, et al., Facile syntheses for (5Z,(9Z)-5,9-hexadecadienoic acid, (5Z,9Z)-5,9-nonadecadienoic acid, and (5Z,9Z)-5,9-eicosadienoic acid through a common synthetic route. Chem Phys Lipids. 1999 Jul;100(1-2):33-40.
Carballeira NM, et al., 5,9-Nonadecadienoic acids in malvaviscus arboreus and allamanda cathartica. Phytochemistry. 1998 Nov;49(5):1253-1256.
Mizushina Y, et al., The inhibitory action 14,15 of fatty acids on DNA polymerase beta. Biochemica et Biophysica Acta. 1997 Oct;1336(3):509-521.
Pariza, MW, et al., The biologically active isomers of conjugated linoleic acid. Prog Lipid Res. 2001 Jul;40(4):283-98.
Database WPI, Section Ch, Week 198421, Derwent Publications Ltd., London, GB; 1994 Apr.
Beerthuis et al., “Synthesis of a Series of Polyunsaturated Fatty Acids, Their Potencies as Essential Fatty Acids and as Precursors of Prostaglandins”, Recl. Trav. Chim. Pavs-Bas 90:943-960 (1971).
Fretland et al., “The Long Duration in vivo, Inhibition of Prostaglandin Synthetase by 2-Methyl-8CIS-12-Trans-14-CIS-Eicosatrien Oic Acid”, Biochem. Pharmacol. 34 (12):2103-2107 (1985).
Nugteren, D.H., “Inhibition of Prostaglandin Biosynthesis by 8CIS, 12Trans, 14CIS-Eicosatrienoic Acid and 5CIS, 8CIS, 12 Trans, 14CIS Eicosatetraenoic Acid”, Biochim. Biophys. Acta 210(1):171-176 (1970).
Nugteren et al., “Naturally Occurring Conjugated Octadecatrienoic Acids are Strong Inhibitors of Prostaglandin Biosythesis”, Prostaglandins 33(3):403-417 (1987).
Cook Mark E.
Li Guangming
Pariza Michael W
Park Yeonhwa
Henley III Raymond J.
Quarles & Brady LLP
Wisconsin Alumni Research Foundation
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