Conjugate obtained by coupling a lectin and a specific ligand, c

Details Conjugate obtained by coupling a lectin and a specific ligand, c Conjugate obtained by coupling a lectin and a specific ligand, c

1981-05-20

1985-07-02

Nucker, Christine M.

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

Utilizing isolate of tissue or organ as binding agent

436542, 436532, 436800, 436804, 436827, 435 7, G01N 3354, G01N 3358, G01N 3360

Patent

active

045268711

ABSTRACT:
The present invention relates to a conjugate of a specific ligand and a lectin, by covalent bonding.
The product of the invention may, for example, be the conjugate of Concanavalin A and an antigen, a hapten, an antibody, a hormone or its receptor, an enzyme or its inhibitor or a lectin. Coupling being effected by means of glutaraldehyde or p-benzoquinone.

REFERENCES:
patent: 4289747 (1981-09-01), Chu
Guesdon et al, J. Immunol. Methods, 39 (1980) 1-13.
Stratis Avrameas, "Coupling of Enzymes to Proteins with Glutaraldehyde", 1969, Immunochemistry, pp. 43-47.

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