Conjugate including a sugar and peptide linker

Details Conjugate including a sugar and peptide linker Conjugate including a sugar and peptide linker

1993-05-11

1994-08-30

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an organic...

435177, 435181, 530402, 530403, 530406, 530813, 530816, C12N 1110, C12N 1102, C07K 1710

Patent

active

053427700

ABSTRACT:
The present invention provides a conjugate in essentially pure form comprising a sugar linked to a protein through a peptide linker, wherein said sugar has a reducing terminal and is free of carboxyl groups, and wherein the reducing terminal of said sugar is linked to the peptide linker. The present invention further provides a conjugate in essentially pure form comprising a sugar linked to an enzyme through a peptide linker, wherein said sugar has a reducing terminal and is free of carboxyl groups, and wherein the reducing terminal of said sugar is linked to the peptide linker. The present invention additionally provides a conjugate in essentially pure form comprising a sugar linked to lysozyme through a peptide linker, wherein said sugar has a reducing terminal and is free of carboxyl groups, and wherein the reducing terminal of said sugar is linked to the peptide linker.

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patent: 5037883 (1991-08-01), Kopecek et al.
Stryer (1975) "Biochemistry", 2nd Ed., Freeman & Co., San Francisco, p. 774.

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