Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
1997-10-14
2004-03-16
Levy, Neil S. (Department: 1616)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C424S001690, C424S009600, C424S009610, C424S001530, C514S034000, C514S152000, C514S224200, C514S676000, C514S680000, C514S681000, C514S683000
Reexamination Certificate
active
06706713
ABSTRACT:
This is a national phase filing of the Application No. PCT/DE96/00644, which was filed with the Patent Corporation Treaty on Apr. 12, 1996, and is entitled to priority of the German Patent Application 195 14 088.5, filed Apr. 13, 1995.
I. FIELD OF THE INVENTION
This invention relates to a conjugate comprising an active substance and a native protein which is not recognized as a foreign protein, for the production of a pharmaceutical preparation for treating and/or diagnosing inflammatory, infectious and/or skin diseases.
II. BACKGROUND OF THE INVENTION
Up to the present, pharmaceutical preparations have been used for treating inflammatory, infectious and skin diseases, which are administered in high doses, partially even several times daily. In addition, these pharmaceutical preparations accumulate in many tissues. Thus, they are a major load for the body.
DE-A-41 22 210 discloses a conjugate consisting of a tumor-active compound and a native protein which is not recognized as a foreign protein. This conjugate is used for treating tumor diseases.
Surprisingly, it has now turned out that such a conjugate is also suitable for treating and/or diagnosing inflammatory, infectious and/or skin diseases, the drawbacks of the pharmaceutical preparations, used for this purpose up to the present, not occurring.
III. SUMMARY OF THE INVENTION
This invention relates to the use of a conjugate comprising an active substance and a native protein which is not recognized as foreign protein for the production of a pharmaceutical preparation for treating and/or diagnosing inflammatory, infectious and/or skin diseases.
REFERENCES:
patent: 4767745 (1988-08-01), Young et al.
patent: 4926869 (1990-05-01), Rubin et al.
patent: 5051406 (1991-09-01), Satoh
patent: 5171749 (1992-12-01), Levy et al.
patent: 0 282 057 (1988-09-01), None
patent: 0326618 (1989-08-01), None
patent: 0 326 618 (1989-08-01), None
patent: 0 352 076 (1990-01-01), None
patent: 0352076 (1990-01-01), None
patent: 0601183 (1994-06-01), None
patent: 0 601 183 (1994-06-01), None
patent: 0 649 857 (1995-04-01), None
patent: 63 267 734 (1988-11-01), None
patent: 63267734 (1988-11-01), None
patent: WO 87/04351 (1987-07-01), None
patent: WO 93/23743 (1993-11-01), None
patent: WO 95/12414 (1995-05-01), None
The Use of Protein—pp. 329-342, Aurej et al in Neoplasma 35, 3, 1988.*
Goldenberg H, Abstract of WO9404702, 3/94.*
Byres et al, Neoplasma, 35(3) 329-42, 88.*
Chem Abstracts vol. 124 #6,5 # 66584, Mukhopadhyay et al. A Process for the Preparation—2/96.*
Int. J. of Radiation—Bd. 18, Nr. 6, Thakur et al. Technetium-99-m-labelled Proteins—Jan. 1, 1991.*
J. of Fluorescence Bd. 3, Nr. 3, Terpetshnig et al. An Investigation of Squarainers—Sep. 1, 1993.*
J. of Pharmaceutical Sciences Bd. 66, Nr. 3, Hare et al., Analysis of Sulindac & Metabolites—3/77.*
Mukhopadhyay et al., 1989, “Receptor-Mediated Drug Delivery to Macrophages in Chemotherapy of Leishmaniasis,”Science 244: 705-707.
Weinblatt, 1995, “Methotrexate for Chronic Diseases in Adults,”The New England Journal of Medicine 332(5):330-331.
Maier-Borst Wolfgang
Schrenk Hans-Hermann
Sinn Hansjörg
Stehle Gerd
Deutsches Krebsforschungszentrum Stiftung des Offentlichen Recht
Levy Neil S.
Pennie & Edmonds LLP
LandOfFree
Conjugate for treating inflammatory infectious and/or skin... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Conjugate for treating inflammatory infectious and/or skin..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Conjugate for treating inflammatory infectious and/or skin... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3245191