Conjugate addition reactions for the controlled delivery of...

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S006120, C435S188000, C424S094300, C424S177100, C424S181100, C536S024100

Reexamination Certificate

active

07413739

ABSTRACT:
The invention features polymeric biomaterials formed by nucleophilic addition reactions to conjugated unsaturated groups. These biomaterials may be used for medical treatments.

REFERENCES:
patent: 4618400 (1986-10-01), Wood
patent: 4711903 (1987-12-01), Mueller et al.
patent: 5268305 (1993-12-01), Ribi et al.
patent: 5292514 (1994-03-01), Capecchi et al.
patent: 5294690 (1994-03-01), Iguchi et al.
patent: 5330911 (1994-07-01), Hubbell et al.
patent: 5410016 (1995-04-01), Hubbell et al.
patent: 5427915 (1995-06-01), Ribi et al.
patent: 5428014 (1995-06-01), Labroo et al.
patent: 5446090 (1995-08-01), Harris
patent: 5529914 (1996-06-01), Hubbell et al.
patent: 5567422 (1996-10-01), Greenwald
patent: 5573934 (1996-11-01), Hubbel et al.
patent: 5575815 (1996-11-01), Slepian et al.
patent: 5612390 (1997-03-01), Iguchi et al.
patent: 5635207 (1997-06-01), Grinstaff et al.
patent: 5648506 (1997-07-01), Desai et al.
patent: 5702717 (1997-12-01), Cha et al.
patent: 5752974 (1998-05-01), Rhee et al.
patent: 5801033 (1998-09-01), Hubbell et al.
patent: 5817840 (1998-10-01), Nicolaou et al.
patent: 5852182 (1998-12-01), Cook et al.
patent: 5858746 (1999-01-01), Hubbell et al.
patent: 5874500 (1999-02-01), Rhee et al.
patent: 5880131 (1999-03-01), Greenwald et al.
patent: 5897955 (1999-04-01), Drumheller
patent: 5932462 (1999-08-01), Harris et al.
patent: 5958874 (1999-09-01), Clark et al.
patent: 5965588 (1999-10-01), Vasquez et al.
patent: 6136564 (2000-10-01), Kopetzki et al.
patent: 2003/0044468 (2003-03-01), Cellesi et al.
patent: 2003/0059906 (2003-03-01), Hubbell et al.
patent: 2281602 (1998-08-01), None
patent: 1348045 (1974-03-01), None
patent: WO 95/13312 (1995-05-01), None
patent: WO 97/22371 (1997-06-01), None
patent: WO 98/32466 (1998-07-01), None
patent: WO 99/14259 (1999-03-01), None
patent: WO 99/22770 (1999-05-01), None
patent: WO 99/34833 (1999-07-01), None
patent: WO 00/09087 (2000-02-01), None
patent: WO 00/44808 (2000-08-01), None
patent: WO 01/02017 (2001-01-01), None
patent: WO 03/040235 (2003-05-01), None
Ballini et al., “Amberlyst A-27, an Efficient Heterogeneous Catalyst for the Michael Reactions of Nitroalkanes with β-Substituted Alkene Acceptors,”J. Org. Chem. 61:3209-3211, 1996.
Boyland et al., “Enzymes Catalysing Conjugations of Glutathione with Alpha-beta-unsaturated Carbonyl Compounds,”Biochem. J. 109:651-661, 1968.
Chasseaud, “Distribution of Enzymes that Catalyse Reactions of Glutathione with Alpha Beta-unsaturated Compounds,”Biochem. J. 131:765-769, 1973.
Eisele et al., “Kinetics of Photcrosslinking Reactions of a DCPA/EA Matrix in the Presence of Thiols and Acrylates,”J. Polym. Sci., Polym. Chem. Ed. 35:2333-2345, 1997.
Fan et al., “Molecular Recognition and Catalysis: Incorporation of an □Oxyanion Hole□ into a Synthetic Receptor,”New J. Chem. 21(1):81-85, 1997.
Friedman et al., “Relative Nucleophilic Reactivities of Amino Groups and Mercaptide Ions in Addition Reactions with α,β-Unsaturated Compounds,”J. Am. Chem. Soc. 87(16):3672-3682, 1965.
Ghandehari et al., “In Vitro Degradation of pH-sensitive Hydrogels Containing Aromatic Azo Bonds,”Biomaterials18:861-872, 1997.
Hern et al., “Incorporation of Adhesion Peptides into Non-adhesive Hydrogels Useful for Tissue Resurfacing,”J. Biomed. Mater. Res. 39:266-276, 1998.
Hirai et al., “pH-induced Structure Change of Poly(vinly alcohol) Hydrogel Crosslinked with Poly(acrylic acid),”Die Angewandte Makromolekulare Chemie240:213-219, 1996.
Ishihara et al., “Tris(pentafluorphenyl)boron as an Efficient, Air Stable, and Water Tolerant Lewis Acid Catalyst,”Bull. Chem. Soc. Jpn. 68:1721-1730, 1995.
Kawai et al., “New Application of Solid Acid to Carbon-Carbon Bond Formation Reactions: Clay Montmorillonite-Catalyzed Aldol Reactions of Silyl Enol Ethers with Aldehydes and Acetals,”Bull. Chem. Soc. Jpn. 61:1237-1245, 1988.
Kito et al., “Biocompatible Coatings for Luminal and Outer Surfaces of Small-caliber Artificial Grafts,”Journal of Biomedical Materials Research30:321-330, 1996.
Mathur et al., “Methods for Synthesis of Hydrogel Networks: A Review,”Journal of Macromolecular Science-Reviews in Macromolecular Chemistry and PhysicsC36(2):405-430, 1996.
Moghaddam et al., “Molecular Design of 3-Dimensional Artificial Extracellular-matrix—Photosensitive Polymers Containing Cell Adhesive Peptide,”Journal of Polymer Science: Part A: Polymer Chemistry31:1589-1597, 1993.
Morpurgo et al., “Preparation and Characterization of Poly(ethylene glycol) Vinyl Sulfone,”Bioconjugate Chem. 7:363-368, 1996.
Pato et al., “Polymers Containing Enzymatically Degradable Bonds, 9a)Chymotrypsin Catalyzed Hydrolysis of a p-nitroanilide Drug Model, Bound Via Oligopeptides onto Poly(vinylpyrrolidone-co-maleic anhydride),”Makromol. Chem. 185:231-237, 1984.
Pathak et al., “Rapid Photopolymerization of Immunoprotective Gels in Contact with Cells and Tissue,”Journal of the American Chem. Society114:8311-8312, 1992.
Petka et al., “Reversible Hydrogels from Self-Assembling Artificial Proteins,”Science281:389-392, 1998.
Romanowska et al., “Michael Additions for Syntheses of Neoglycoproteins,”Methods in Enzymol. 242:90-101, 1994.
Sawhney et al., “Bioerodible Hydrogels Based on Photopolymerized Poly(ethylene glycol)-co-poly(α-hydroxy acid) Diacrylate Macromers,”Macromolecules26:581-587, 1993.
Tanaka et al., “Michael-type Addition of Illudin S, a Toxic Substance fromLampteromyces japonicus, with Cysteine and Cysteine-containing Peptides In Vitro,”Chem. Pharm. Bull. 44:273-279, 1996.
West et al., “Comparison of Covalently and Physically Cross-linked Polyethylene Glycol-based Hydrogels for the Prevention of Postoperative Adhesions in a Rat Model,”Biomaterials16:1153-1156, 1995.
Zhao et al., “Novel Degradable PEG Esters for Drug Delivery: Synthesis and Characterization,”Polymer Reprints38:526-527, 1997.
Baker, “Controlled Release of Biologically Active Agents,” Bruck, ed., p. 84-131 John Wiley and Sons, New York (1987).
Deutsch et al., “Synthesis of Congeners and Prodrugs. 3. Water-Soluble Prodrugs of Taxol with Potent Antitumor Activity,”Journal of Medicinal Chemistry32:788-792 (1989).
Dumitriu et al., “Polymeric Drug Carriers,” InPolymeric Biomaterials, Dumitriu, ed., p. 435-449 and 466-724, Marcel Dekker, New York (1994).
Duncan et al., “Soluble Synthetic Polymers and Potential Drug Carriers,”Adv. In Polym. Sci. 57:51-101 (1984).
Greenwald et al., “Drug Delivery Systems: Water Soluble Taxol-2′-Poly(ethylene glycol) Ester Prodrugs-Design and in Vivo Effectiveness,”J. Med. Chem. 39:424-431 (1996).
Lau et al., “Conjugation of Doxorubicin to Monoclonal Anti-carcinoembryonic Antigen Antibody via Novel Thiol-directed Cross-linking Reagents,”Bioorganic&Medicinal Chemistry3:1299-1304 (1995).
Lau et al., “Novel Doxorubicin-Monoclonal Anti-carcinoembryonic Antigen Antibody Immunoconjugate Activity in vitro,”Biorganic&Medicinal Chemistry3:1305:1312 (1995).
Morpurgo et al., “Preparation and Characterization of Poly(ethylene glycol) Vinyl Sulfone,”Bioconjugate Chem. 7:363-368 (1996).
Pitt et al., “Controlled Drug Delivery,”InBiodegradation of Polymers, Basic Concepts, vol. 1, p. 53-80, CRC Press, Boca Raton, Florida (1983).
Wright et al.,The Chemistry and Pharmacology of Taxol and Its Derivatives, Farina, ed., p. 110-130 and 165-300, Elsevier, New York (1995).
Zalipsky et al., “Attachment of Drugs to Polyethylene Glycols,”Eur. Polym. J. 19:1177-1183 (1983).
Aida et al., “Zinc N-substituted Porphyrins as Novel Initiators for the Living and Immortal Polymerizations of Episulfide,” Macromolecules, 23:3887-3892 (1990).
Blume et al., “Specific

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Conjugate addition reactions for the controlled delivery of... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Conjugate addition reactions for the controlled delivery of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Conjugate addition reactions for the controlled delivery of... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3993352

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.