Conformationally restricted HIV-1 protease inhibitors

Details Conformationally restricted HIV-1 protease inhibitors Conformationally restricted HIV-1 protease inhibitors

1994-03-29

1996-04-30

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514314, 514317, 514319, 514320, 514324, 514326, 514327, 514422, 514424, 546164, 546192, 546202, 546206, 546207, 546213, 546217, 548518, 548525, 548544, 548952, A61K 31445, A61K 3147, C07D21140, C07D207273

Patent

active

055125603

ABSTRACT:
HIV protease inhibitors containing hydroxypyrrolidine or hydroxypiperidine with one or more basic amines are disclosed.

REFERENCES:
Kohl et al., Proc. Natl. Acad. Sci., vol. 85, p. 4686 (1988).
Ratner et al., Nature,vol. 313, p. 297, (1985).
Toh et al., EMBO., vol. 4, p. 1267 (1985).

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