Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-12-25
2007-12-25
Seaman, Margaret D. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
Reexamination Certificate
active
11035037
ABSTRACT:
Constrained paclitaxel derivatives include a bridge extending from the C-3′ phenyl to either the C4 or -3 positions. Many of the constrained paclitaxel derivatives provide activity comparable or superior to the natural product paclitaxel.
REFERENCES:
Freshnet et al., Culture of animal cells, A manual of basic technique, Alan R. Liss, Inc., 1983, New York, pp. 1-6.
Dermer et al., Bio/lechnology, 1994, 12:320.
Liu et al., “Syntheses and bioactivities of macrocyclic paclitaxel bis-lactones”, Bioorganic & Medicinal Chemistry, 2004, vol. 12, pp. 6147-6161.
Synthesis and Biological Evaluation of Novel Macrocyclic Paclitaxel Analogues, B. Metaferia, et al. Department of Chemistry, Virginia Polytechnic Institute and State University, Blacksburg, Virginia; Organic Letters, 2001 vol. 3, No. 16; pp. 2461-2464.
Bane Susan Lynn
Ganesh Thota
Kingston David George Ian
Lakdawala Ami S.
Synder James Patrick
Binghamton University
Emory University
Rahmani Niloofar
Seaman Margaret D.
Virginia Tech Intellectual Properties Inc.
LandOfFree
Conformationally constrained paclitaxel analogs and their... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Conformationally constrained paclitaxel analogs and their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Conformationally constrained paclitaxel analogs and their... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3866789