Confocal imaging through thick dermal tissue

Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation

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600473, A61B 500

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active

057886393

ABSTRACT:
A handheld confocal imaging system for in vivo observation of dermal and subdermal tissue allows diagnosis of conditions substantially beneath the surface of the skin. A confocal head has optics which scan the tissue so as to provide images of vertical sections of the tissue. Both two and three dimensional imaging may be provided for diagnosis and location of basal cell carcinomas and melanomas, and so as to enable visualization of tumor borders prior to excision.

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Milind Rajadhyaksha et al., "In Vivo Confocal Scanning Laser Microscopy of HumanSkin: Malanin Provides Strong Contrast",The Journal of Investigative Dermatology, vol. 104, No. 6 Jun. 1995.
Small Business Innovation Research Prog; issued Sep. 28, 92; Grant No. SSS-3 (BA) 1 R43 RRo7737-01; awarded by National Center for Research Resources; entitled Confocal Laser Scanning Microscope--Video, Vector & Zoom.

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