Conditioned medium useful for sustaining growth of colonic crypt

Details Conditioned medium useful for sustaining growth of colonic crypt Conditioned medium useful for sustaining growth of colonic crypt

1992-03-16

1994-05-31

Robinson, Douglas W.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

4352402, 435 703, C12N 500

Patent

active

053169379

ABSTRACT:
The invention describes a colonic crypt cell stimulating mitogen, and conditioned medium containing it. In particular, cell line LIM 2537 is described which, when cultivated in medium, secretes a mitogen which stimulates the proliferation o colonic crypt cells. Applications of the conditioned medium and the cell line are also described.

REFERENCES:
Whitehead et al, In Vitro Cell & Dev. Biology, 23 (6), pp. 436-442, Jun. 1987.
Whitehead et al, Int. J. Cancer, 46, pp. 858-863, 1990.
Nice et al, J. of Biological Chemistry, 266 (22), pp. 14425-14430, Aug. 5, 1991.
ATCC Catalogue of Cell Lines & Hybridomas, 6th edition, 1988, p. 354.

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