Condensed pyrazole derivatives, process for producing the...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C544S126000, C544S333000, C546S083000

Reexamination Certificate

active

06949648

ABSTRACT:
Novel pharmaceutical compositions for inhibiting Th2-selective immune response and pharmaceutical compositions for inhibiting cyclooxygenase comprising condensed pyrazole derivatives represented by the general formula (I):or salts thereof.

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Compounds with RN 113576-39-9 and 114072-97-8 ( disclosed in a Russian Journal, Vysokochistye Veshchestva (1987 ).
Ostrovskaya, V., et al.,“Analytically ready forms and reagents for their preparation. I. Immobilization of pyrazolyl-containing formazans and hydrazones on a paper base for rapid tests as a means for achieving . . . ”,Vysokochistye Veshchestva(1987), vol. 4, pp. 178-182 (English Abstract Only).
Harry R. Snyder, Jr., “1H-Pyrazolo[3,4-b]pyridines” J. Heterocycle Chem. 12(6):1303-1304 (1975).
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Y. Tominaga, et al. “Synthesis and Chemiluminescence of 1,3-Disubstituted Pyrazolo[4′,3′:5,6]Pyrido[2,3-d]Pyridazine-5,8(6H,7H)-Diones and Related Compounds” Tetrahedron Letters 36(47): 8641-8644(1995).
Farghaly, et al. “Synthesis of Some Thiazole-, 1,34-Thiadiazole-, and 4H-1,2,4-Triazole Derivatives of Pyrazolo[3,4-b]quinoline”.
Nielsen, et al. “Synthesis of 4-Arylamino-5,6,7,8-tetrahydro-1H-pyrazolo[3,4-b]quinolines and the Corresponding N-Mannich Bases” Liebigs Ann. Chem. 1728-1735(1986).
Tomasik, et al. “Friedländer Condensation of 1H-Pyrazolin-5-ones with o-Aminobenzaldehydes. Synthesis of 1H-Pyrazolo[3,4-b]quinolines” J. Heterocyclic Chem. 20: 1539-1543 (1983).
Kidwai, et al. “Synthesis of Some Novel Substituted Quinolines as Potent Analgesic Agents” Monatshefte Fur Chemie 128: 85-89(1997).

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