Condensed heterocyclic compounds, their production and use

Details Condensed heterocyclic compounds, their production and use Condensed heterocyclic compounds, their production and use

1991-12-16

1993-12-07

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 17, 514 18, 530329, 530330, 530331, A61K 3702, C07K 506

Patent

active

052683621

ABSTRACT:
A novel compound of the formula: ##STR1## wherein a ring A stands for an optionally substituted 5-membered ring; B stands for an optionally substituted divalent cyclic or chain group; either one of Q.sup.1 and Q.sup.2 stands for N and the other stands for N or CH; X stands for an amino group, hydroxyl group or mercapto group; Y stands for H, halogen atom or a group bonded through C, N, O or S; Z stands for a straight-chain divalent group having 2 to 5 atoms constituted of optionally substituted carbon atoms or constituted of optionally substituted carbon atoms and one optionally substituted hetero-atom; COOR.sup.1 and COOR.sup.2 independently stand for an optionally esterified carboxyl group; n denotes an integer of 2 to 6; and R.sup.1 may be different in each of n repeating units, or their salts and it is useful as a therapeutic drug for tumor in mammals.

REFERENCES:
patent: 4996206 (1991-02-01), Taylor et al.
patent: 4997838 (1991-03-01), Akimoto et al.
patent: 5028608 (1991-07-01), Taylor et al.
Catalog Handbook of Fine Chemicals by Aldrich, pp. 297-298, pp. 738-739.

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