Condensed heterocyclic compounds, their production and use

Details Condensed heterocyclic compounds, their production and use Condensed heterocyclic compounds, their production and use

1993-08-27

1995-10-17

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 18, 514 19, 514253, 514254, 514255, 514256, 514299, 514300, 514301, 514302, 514303, 530329, 530330, 530331, 544278, 544280, 546114, 546115, 546116, 546117, 546118, 546119, 546120, A61K 3805, A61K 3806, A61K 3807, A61K 3808

Patent

active

054591295

ABSTRACT:
A novel compound of the formula: ##STR1## wherein a ring A stands for an optionally substituted 5-membered ring; B stands for an optionally substituted divalent cyclic or chain group; either one of Q.sup.1 and Q.sup.2 stands for N and the other stands for N or CH; X stands for an amino group, hydroxyl group or mercapto group; Y stands for H, halogen atom or a group bonded through C, N, 0 or S; Z stands for a straight-chain divalent group having 2 to 5 atoms constituted of optionally substituted carbon atoms or constituted of optionally substituted carbon atoms and one optionally substituted hetero-atom; COOR.sup.1 and COOR.sup.2 independently stand for an optionally esterified carboxyl group; n denotes an integer of 2 to 6; and R.sup.1 may be different in each of n repeating units, or their salts and it is useful as a therapeutic drug for tumor in mammals.

REFERENCES:
patent: 4996206 (1991-02-01), Taylor et al.
patent: 4997838 (1991-03-01), Akimoto et al.
patent: 5028608 (1991-07-01), Taylor et al.
Catalog Handbook of Fine Chemicals by Aldrich, pp. 297-298 & 738-739.

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