Condensation of substituted phenylacetonitriles with dicarboxyli

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07C12176

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active

044709293

ABSTRACT:
This invention relates to the stoichiometric condensation of substituted phenylacetonitriles with dibasic carboxylic anhydrides. The resulting cyano-keto-acids are obtained in good yield and can be used to prepare biologically active 2-aryl-1,3-cyclohexanediones without elaborate purification.

REFERENCES:
patent: 4175135 (1979-11-01), Haines
patent: 4256657 (1981-03-01), Wheeler
patent: 4422870 (1983-12-01), Wheeler
V. Oskaja et al., C.A., 56, 10029, (1962).
P. Hrneiar, C.A., 60, 4053, (1964).
Hannout et al., J. fus Prakt Chem., 316, 463, (1974).

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