Concentrating nikkomicin mixtures

Details Concentrating nikkomicin mixtures Concentrating nikkomicin mixtures

1983-05-26

1985-11-12

Love, Ethel G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C07H 1700

Patent

active

045529540

ABSTRACT:
A process for concentrating nikkomicins (X) and (Z) from a dilute impure aqueous solution thereof, comprising contacting the solution with a weakly basic ion exchanger and eluting the adsorbed material with an acid thereby to obtain a concentrated mixture of nikkomicin (X) and nikkomicin (Z). The dilute solution being treated can directly be a filtered microbial cultivation liquor or such a liquor can be prepurified by contact with an acid ion exchanger followed by elution with a base. The recovered material is of relatively high purity.

REFERENCES:
patent: 4287186 (1981-09-01), Zahner et al.
patent: 4315922 (1982-02-01), Hagenmaier et al.
patent: 4402947 (1983-09-01), Moeschler et al.

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