Concentrated, stabilized cis-diamminedinitratoplatinum solutions

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Heavy metal or compound thereof

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A61K 3324

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active

049466895

ABSTRACT:
The invention relates to chemically stable, concentrated solutions of cis-diamminedinitratoplatinum which are pH-stabilized with nitric acid and are readily convertible to parenteral cisplatin solutions by addition of sources of chloride ion.

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Faggiani et al., J. of the American Chemical Society, 99:3 (1977) discloses the crystalline structure and vibrational.
Lippert et al., Inorganic Chemistry, vol. 10, 1525 (1977).
King, Journal of Chemical Society, (1938), 1338-1346.

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