Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1992-04-24
1993-11-09
Schain, Howard E.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
530381, A61K 3516, A61K 914
Patent
active
052604209
ABSTRACT:
The invention provides a thrombin coagulable protein concentrate,, the preparation thereof and the therapeutic use thereof. This concentrate has a fibrinogen content greater than 70% and a sufficient amount of endogenous Factor XIII. It may be solubilized at ambient temperature. Its preparation comprises at least one cold precipitation step with dilute ethanol and uses total plasma as a starting product. The concentrate of the invention makes it possible more particularly to obtain an injectable fibrinogen and a biological glue of high quality.
REFERENCES:
patent: 4362567 (1982-12-01), Schwarz et al.
patent: 4374061 (1983-02-01), Bing
patent: 4377572 (1983-03-01), Schwarz et al.
patent: 4427650 (1984-01-01), Stroetmann
patent: 4568545 (1986-04-01), Mihara et al.
patent: 4613501 (1986-09-01), Horowitz
patent: 4627879 (1986-12-01), Rose et al.
patent: 4640834 (1987-02-01), Eibl et al.
Quinn et al. (1983), Abstract, J. Pharm. Sci. 72, 1472.
Biological Abstracts, vol. 77, No. 7, 1984, resume No. 49207, Philadelphia, U.S., M. G. Ikossi-O'Connor et al: "The Role of Fibrin Adhesive in Vascular Surgery".
Burnouf Thierry
Burnouf-Radosevich Miryana
Centre Regional de Transfusion Sanguine de Lille
Schain Howard E.
Touzeau P. Lynn
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