Image analysis – Applications – Biomedical applications
Reexamination Certificate
2007-05-29
2007-05-29
Bella, Matthew C. (Department: 2624)
Image analysis
Applications
Biomedical applications
C356S518000
Reexamination Certificate
active
09856422
ABSTRACT:
Apparatus for computational adaptive imaging comprises the following: an image information acquirer, which provides information relating to the refractive characteristics in a three-dimensional imaged volume; a ray tracer, which uses the information relating to the refractive characteristics to trace a multiplicity of rays from a multiplicity of locations in the three-dimensional imaged volume through the three-dimensional imaged volume, thereby providing a location dependent point spread function, and a deconvolver, which uses the location dependent point spread function, to provide an output image corrected for distortions due to variations in the refractive characteristics in the three-dimensional imaged volume.
REFERENCES:
patent: 4362943 (1982-12-01), Presby
patent: 4720633 (1988-01-01), Nelson
patent: 4827125 (1989-05-01), Goldstein
patent: 4880976 (1989-11-01), Mancuso et al.
patent: 4947323 (1990-08-01), Smith
patent: 5412211 (1995-05-01), Knowles
patent: 5671136 (1997-09-01), Willhoit, Jr.
patent: 5783833 (1998-07-01), Sugaya et al.
patent: 5787146 (1998-07-01), Giebeler
patent: 5789748 (1998-08-01), Liu et al.
patent: 5912257 (1999-06-01), Prasad et al.
patent: 6084227 (2000-07-01), Rhoads
patent: 6166853 (2000-12-01), Sapia et al.
patent: 6275726 (2001-08-01), Chan et al.
patent: 6384952 (2002-05-01), Clark et al.
patent: 6459482 (2002-10-01), Singh et al.
patent: 6658142 (2003-12-01), Kam et al.
patent: 6771417 (2004-08-01), Wolleschensky et al.
Jos Stam et al., Ray Tracing in Non-Constant Media, Rendering Techniques 96, Proceedings of the 7thEurographics Worksho on Rendering, 1996.
Marc Berger et al., Ray Tracing, IEEE Computer Graphics & Applications, 1990, pp. 36-41.
N.C. Schoen, Ray Tracing Analysis for Media with Nonhomogeneous Indices of Refraction, Optical Society of America, vol. 12, No. 18, Applied Optics, Sep. 15, 1982, pp. 3329-3331.
Farhana Kagalwala et al., Computational model of DIC microscopy for reconstructing 3-D specimens: from observations to measurement, Conference on Three-dimensional and multidimensional, San Jose CA, Jan. 27-29, 1998,pp. 35-36.
N. S. White et al., Aberration control in quantitative imaging of botanical specimens by multidimensional fluorescence microscopy, Journal of Microscopy, vol. 181, Pt. 2, Feb. 1996, pp. 99-116.
Pratt, W.K. “Digital Image Processing”, NY John Wiley & Sons, Inc., (1991).
Rosenfeld, A and Kak, A.C. “Digital Picture Processing”, Academic Press. (1976).
Castleman, K.R. “Digital Image procssing”, Prentice-Hall inc., Englewood Cliffs, New Jersey. (1979).
Inoui, S. and Spring, K.S. “Video Microscopy; The Fundamentals”, 2nd Edition, Plenum Press, NY (1997).
Tanford, C. “Physical Chemistry of Macromolecules”, John Wiley NY. (1961).
Allen R.D. et al., “Video-Enhanced Contrast, Differential Interference Contrast (Avec-Dic), Microscopy: A New Method Capable of Analyzing Microtuble Related Motility in the Reticulopodial Network of Allogromia Laticollaria”, Cell Motility 1:291-302 (1981).
Cogswell, C.J. et al., “Confocal Differential Interference Contrast (DIC) Microscopy: Including a Theoretical Analysis of Conventional and Confocal DIC Imaging”, J. Microsc. 165:81-101 (1992).
Gelles, J. et al., “Tracking Kinesin-Driven Movements with Nanometre-Scale Precision”, Nature 331:450-453 (1988).
Ha-usler, G. et al., “Imaging with Expanded Depth of Focus”, Zeiss Inform. 29:9-13 (1987).
Preza, C. et al., “Image Reconstruction for Three-Dimensional Transmitted Light DIC Microscopy”, SPIE 2984:220-231 (1997).
Schormann, T. et al., “Contrast Enhancement and Depth Perception in Three-Dimensional Representations of Differential Interference Contrast and Confocal Scanning Laser Microscope Images”, J.Microsc. 166:155-168 (1992).
Jenkins, F.A. et al., “Fundamentals of Optics”, McGraw-Hill, NY (1950) CH.8: Ray Tracing.
Born M. et al., “Principles of Optics”, Pergamon London (1959).
Goodman J.W. “Statistical Optics”, John Wiley & Sons NY (1985).
Gibson S.F. et al., “Modeling Aberrations Due to Mismatched Layers for 3-D Microscopy” SPIE Optics in Complex Systems 1319:470-471 (1990).
Gibson S.F. et al., “Experimental Test of an Analytical Model of Abberation in an Oilimmersion Objective Lens Used in Three-Dimensional Light Microscopy”, J. Opt. Soc. Am. A8:1601-1613 (1991).
Jansson, P.A. ed. “Deconvolution of Images and Spectra”, Academic Press NY (1997).
Agard, D.A. et al., “Three-Dimensional Architecture of a Polytene Nucles”, Nature 302:676-681 (1984).
Agard, D.A. et al., “Fluorescence Microscopy in Three Dimensions”, Methods in Cell Biology 30:353-377 (1989).
Boden, A.F. et al., “Comparative Results with Massively Prallel Spatially Variant Maximum Likelihood Image Restoration”, Bul Am Astr. Soc. 27:924-929 (1995).
Boden, A.F. et al., “Massively Parallel Spatially-Variant Maximum Likelihood Restoration of Hubble Space Telescope Imagery”, J.Opt Soc Am A 13:1537-1545 (1996).
Tyson R.K. “Principles of Adaptive Optics”, Academic Press NY (1991).
Carrington, W.A. et al., “Superresolution Three Dimensional Images of Fluorescence in Cells with Minimal Light Exposure”, Science 268:1483-1487 (1995).
Femino, A.M. et al., “Visualization of Single RNA Transcripts in Situ”, Science 280:585-590 (1998).
Z, Kam, “Microscopic Differential Interference Contrast Image Processing by Line Integration (LID) and Deconvolution”, Bioimaging 6(4): 166-176 (1998).
Nomarski's DIC Microscopy: A Review, Institute of Applied Optics, SPIE 1846:10-25 (1994).
Scalettar, B.A. et al., “Dispersion, Aberration and Deconvolution in Multi-Wavelength Fluorescence Images”,Journal of Microscopy, vol. 182, No. 1, Apr. 1996, pp. 50-60.
Patent Abstracts of Japan, vol. 1997, No. 8, Aug. 1997.
Agard, D. et al., “Three-Dimensional Microscopy: Image Processing for High Resolution Subcellular Imaging”,New Methods in Microscopy and Low Light Imaging, USA, Aug. 1989, vol. 1161, pp. 24-30.
Z. Kam, et al., “Computational Adaptive Optics for Live Three-Dimensional Biological Imaging”, PNAS, Mar. 27, 2001, vol. 98, No. 7, pp. 3790-3795.
Agard David A
Hanser Bridget M
Kam Zvi
Sedat John W
Bella Matthew C.
Ladas and Parry LLP
Lu Tom Y.
The Regents of the University of California
Yeda Research and Development Co. Ltd.
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