Computer method and apparatus for uniform representation of...

Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Biological or biochemical

Reexamination Certificate

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C702S019000, C435S006120, C707S793000, C536S023100

Reexamination Certificate

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07047137

ABSTRACT:
A method and apparatus transforms typically differing length text string representations (i.e., sequences) of biological fragments into uniform length representations. A comparison database stores a predefined number of known biological sequences. A comparison routine compares and scores a subject sequence against each known sequence in the database. Each individual score (one for each known sequence in the database) serves as a vector element forming a fixed length vector representation of the subject sequence. Vector length equals the predefined number of known biological sequences in the database. Scoring is a probability or an occurrence count of the known biological sequence in the subject sequence.

REFERENCES:
patent: 6453245 (2002-09-01), Rothberg et al.
patent: 6834239 (2004-12-01), Lobanov et al.
patent: 6882990 (2005-04-01), Barnhill et al.
patent: 6904423 (2005-06-01), Nicolaou et al.
patent: 2002/0177138 (2002-11-01), Boissy
Levy et al. “Xlandscape: The graphical display of word frequencies in sequences”. Bioinformatics, 1998, vol. 14, No. 1, pp. 74-80.
Jaakkola et al. “Using the Fisher Kernel Method to Detect Remote Protein Homologies”. Proceedings of the 7thInternational Conference on Intelligent Systems for Molecular Biology (ISBM-99), Heidelberg, GER, pp. 149-158 (1999).
Burges, C.J.C. “A Tutorial of Support Vector Machines for Pattern Recognition”. Data Mining and Knowledge Discovery Journal, vol. 2, No. 2, pp. 121-167 (1998).
Berry et al. Matrices, Vector Spaces and Information Retireval. (Apr. 23, 1999) Society for Industrial and Applied Mathematics Review. 41:2 335-362.
Stuart et al. A comprehensive vertebrate phylogeny using vector representations of protein sequences from whole genomes. Molecular Biology and Evolution. Apr. 2002, vol. 19 :4 554-562.
Akutsu, T. Substructure Search and Alignment Algorithms for Three dimensional Protein Structures. Joho Shori Gakkai Kenkyu Hokoku, (1994) vol. 94, No. 82(AL. 41), pp. 1-8.
Stuart et al. Integrated gene and species phylogenies from unaligned whole genome protein sequences. Bioinformatics. (Jan. 2002) vol. 18 (1) pp. 100-108.
Akutsu et al. Rapid protein fragment search using hash functions based on the fourier transform. CABIOS (1997) vol. 13: 4 pp. 357-364.
Altschul, S. F., et al., “Basic Local Alignment Search Tool,”J. Mol. Biol., 215:403-410 (1990).
Sonnhammer, E. L. L., “Pfam: A Comprehensive Database of Protein Domain Families Based on Seed Alignments,”Proteins: Structure, Function, and Genetics, 28:405-420 (1997).
Krogh, A., et al., “Hidden Markov Models in Computational Biology: Applications to Protein Modeling,”J. of Molecular Biology, 235:1501-1531 (1994).
Human Genome Program, U.S. Department of Energy, “Primer on Molecular Genetics”, Washington, D.C., 1992.
Henikoff, S., and Henikoff, J. G., “Automated Assembly of Protein Blocks for Database Searching,”Nucleic Acids Research, 19(23) :6565-6572 (1991).

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