Computer-implemented biological sequence identifier system...

Data processing: structural design – modeling – simulation – and em – Modeling by mathematical expression

Reexamination Certificate

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C702S020000, C702S179000, C702S193000, C703S011000, C707S793000

Reexamination Certificate

active

07623997

ABSTRACT:
A method of: submitting reference sequences to a taxonomic database to produce taxonomic results; and reporting a taxonomic identification based on the taxonomic results. The reference sequences are the output of genetic database queries that return a score for each reference sequence. A method for processing a biological sequence obtained from an assay by: converting base calls located in a predetermined list of positions within the biological sequence to N; and determining the ratio of single nucleotide polymorphisms in the biological sequence relative to a reference sequence. Each entry in the predetermined list of positions represents the capability of a substance hybridizing to a microarray used to generate the biological sequence. The substance is not the nucleic acid of a target pathogen.

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Wilson et al., “High-density microarray of small-subunit ribosomal DNA probes”Appl. Environ. Microbiol., 68, 2535-2541 (2002).

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