Computer designed stabilized proteins and method for producing s

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364498, 436 89, G06F 1546, G01N 3300

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049087738

ABSTRACT:
Proteins, such as enzymes having enhanced stability are designed through the use of a computer method. The method identifies amino acid residues of a protein which may be replaced with a cysteine residue in order to promote the formation of a protein-stabilizing disulfide bond. The computer-designed, stabilized proteins can be produced using recombinant DNA technology.

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