Plant husbandry – Process
Patent
1995-08-22
1997-07-01
Fox, David T.
Plant husbandry
Process
47DIG3, 47DIG6, 435123, A01G 700, A01G 2300, A01H 700, A01H 302, C12P 1702
Patent
active
056425872
ABSTRACT:
A method for accelerating the growth of Taxus X media `Hicksii` and related Taxus species to enhance the production and recovery of taxol and Taxotere from plant tissues is described. The method includes the steps of increasing the production of biomass by cycling growth periods of Taxus plants within a greenhouse or other enclosed structure, harvests of plant parts and cold storage of the remaining unharvested plants to break dormancy and condition the plant for the next cycle of growth and harvest. After at least several cycles, entire plants are harvested for extraction from all plant parts while other plants are saved for stock plants or reforesting. The collected plant material is prepared for extraction of taxol or Taxotere, compounds used in the treatment of cancer.
REFERENCES:
Borman. Scientists mobilize to increase supply of anticancer drug taxol. C & EN. 11-18. Sep. 2, 1991.
Borman. Anticancer drug: Boost to taxol supply planned. C & EN. 4. Mar. 9, 1992.
Foster et al. Height and growth habit of Norway spruce rooted cuttings compared between two serial propagation cycles. Can. J. For. Res. 19:806-811. 1989.
Lumis and Johnson. Response of container-grown `Hicks` Yew to preplant night lighting. HortSci. 18:438-439. 1983.
McGuire et al. Cold storage of rooted Taxus cuttings on subsequent summer regrowth. J. Environ. Hort. 9:36-37. 1991.
Wise et al. Propagation of Abies fraseri by semidormant hardwood stem cuttings. HortSci. 20:1065-1067. 1985.
Gore Gerald E.
Janes Harry W.
Roman Harry T.
Wittman Wayne K.
Fox David T.
GRoW International Corp.
Kimball Melissa L.
Sutton Ezra
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