Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-10-30
1999-08-10
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142355, 5142372, 514343, 514422, 514423, 544124, 544141, 544143, 544 59, 544186, 544187, 544193, 544194, 544360, 544372, 5462791, 548517, 548518, 548531, 548536, C07D21160, C07D40112, C07D40912, A61K 31445
Patent
active
059359544
ABSTRACT:
The present invention relates to compounds that can maintain, increase, or restore sensitivity of cells to therapeutic or prophylactic agents. This invention also relates to pharmaceutical compositions comprising these compounds. The compounds and pharmaceutical compositions of this invention are particularly well-suited for treatment of multi-drug resistant cells, for prevention of the development of multi-drug resistance, and for use in multi-drug resistant cancer therapy.
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Armistead David M.
Saunders Jeffrey O.
Govindaswamy N.
Haley, Jr. James F.
Rao Deepak R.
Shah Mukund J.
Vertex Pharmaceuticals Incorporated
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