Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-03-27
2007-03-27
Balasubramanian, Venkataraman (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S412000, C514S443000, C514S456000, C514S520000, C514S570000, C544S105000, C548S452000, C549S023000, C549S049000
Reexamination Certificate
active
10281990
ABSTRACT:
The present invention provides a compound consisting of a moiety and a group chemically bonded to said moiety, wherein said moiety contains a compound having low activity following oral administration or its parent scaffold and said group has the following general formula (1):in whichR1represents a hydrogen atom, etc.,R2represents a C1–C7halogenoalkyl group, etc.,m represents an integer of 2 to 14, andn represents an integer of 2 to 7,or enantiomers of the compound, or hydrates or pharmaceutically acceptable salts of the compound or enantiomers thereof. The above compound is advantageous in pharmaceutical use because the group of general formula (1) allows compounds such as anti-estrogenic ones to show a significantly increased activity following oral administration when attached to the parent scaffolds of the compounds.
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Choi Jae-Young
Jo JaeChon
Kanbe Yoshitake
Kim Myung-Hwa
Kwon Hee-An
Balasubramanian Venkataraman
Browdy and Neimark PLLC
Chugai Seiyaku Kabushiki Kaisha
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