Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1998-12-21
2000-10-03
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5462764, 5462804, 548518, 548527, 549 77, 514336, 514422, 514438, 514183, 540450, 540484, A61K 314439, C07D40112
Patent
active
061273910
ABSTRACT:
Compounds of peptide mimetic nature having the general formula I ##STR1## wherein a and b are independently 1 or 2, R.sup.1 and R.sup.2 are independently H or C.sub.1-6 alkyl, G and J are independently, inter alia, aromats, and D and E are independently several different groups are growth hormone secretagogous with improved bioavailability.
REFERENCES:
patent: 5767085 (1998-06-01), Johansen et al.
McDowell et al., Proc. Nat'l. Acad. Sci., USA, Biochem., vol. 92, pp. 11165-11169 (Nov. 1995).
Elias et al., The Endocrine Society, vol. 136, No. 12, pp. 5694-5699 (Dec. 1995).
Ankersen Michael
Hansen Thomas Kruse
Lau Jesper
Lundt Behrend Friedrich
Madsen Kjeld
Aulakh Charanjit S.
Kight John
Novo Nordisk A S
Rozek Carol E.
Zelson Steve T.
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