Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-05-22
1977-01-25
Daus, Donald G.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
424261, C07D45706
Patent
active
040050890
ABSTRACT:
New compounds of the general formula (I) ##STR1## wherein R stands for hydrogen or methyl group,
x y stands for a group of the formula ##STR2## and R.sub.1 stands for a group of the formula (III), (IV) or (V) ##STR3## wherein n is an integer from 4 to 10, ARE PREPARED BY ACYLATING A COMPOUND OF THE GENERAL FORMULA (II), ##STR4## wherein R and x y each have the same meanings as defined above, and R.sub.2 stands for a group of the formula (VI), (VII) or (VIII), ##STR5## with a C.sub.6-12 carboxylic acid or a C.sub.6-12 carboxylic acid halide. The new compounds of the general formula (I) and their acid addition salts can be used as antidepressants and antiserotonine agents with prolonged effects.
REFERENCES:
patent: 2533699 (1950-12-01), Stoll et al.
patent: 2673850 (1954-03-01), Stoll et al.
patent: 2946796 (1960-07-01), Rudmer
patent: 3901893 (1975-08-01), Karacsony et al.
Borsi Jozsef
Csanyi Endre
Mago nee Karacsony Erzsebet
Pik Katalin
Wolf Lajos
Daus Donald G.
Richter Gedeon Vegyeszeti Gyar Rt.
Vaughn Mary C.
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