Compounds with bronchodilator activity

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514826, 549 49, 549 51, 549 58, C07C 6994, C07D20908

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active

050267248

ABSTRACT:
A method is provided for treating patients suffering from or susceptible to bronchoconstriction, particularly for patients suffering from an asthmatic attach which comprises the use of benzothiophene, benzofuran, dihydronaphthalene or indene derivatives represented by formula I ##STR1## wherein each of R.sup.1, R.sup.2, R.sup.3 and R.sup.4 is independently H, (1-4C) alkyl, (1-4C) halogen substituted alkyl, OH, (1-4C) alkoxy, (1-4C) halogen substituted alkoxy, NO.sub.2, CN, halogen, an unsubstituted or (1-4C) alkyl substituted amino group, or wherein two adjacent groups R.sup.1, R.sup.2, R.sup.3 or R.sup.4 together form methylenedioxy;

REFERENCES:
patent: 3910955 (1975-10-01), Chapman et al.
patent: 4158015 (1979-06-01), Paul
patent: 4665206 (1987-05-01), Redpath et al.
patent: 4705782 (1987-11-01), Logan et al.
patent: 4737519 (1988-04-01), Yamashita

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