Compounds with anti-inflammatory activity

Details Compounds with anti-inflammatory activity Compounds with anti-inflammatory activity

2004-04-22

2009-08-25

Badio, Barbara P (Department: 1612)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

C514S183000, C540S114000, C540S467000

Reexamination Certificate

active

07579334

ABSTRACT:
The present invention relates to new compounds represented by Formula I:wherein M represents a macrolide subunit of the substructure II:L represents the chain of the substructure III:in-line-formulae description="In-line Formulae" end="lead"?—X1—(CH2)m-Q-(CH2)n—X2—  IIIin-line-formulae description="In-line Formulae" end="tail"?D represents the steroid or nonsteroidal subunit derived from steroid or nonsteroidal (NSAID) drugs with anti-inflammatory activity;The present invention relates also to pharmaceutically acceptable salts and solvates of such prepared compounds, to process and intermediates for their preparation, as well as to the improved therapeutic action and the use in the treatment of inflammatory diseases and conditions in humans and animals.

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