Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Patent
1995-01-27
1997-08-12
Schain, Howard E.
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
4352351, 435375, 530324, 514 12, C12N 508, A61K 3816
Patent
active
056564805
ABSTRACT:
This invention relates to human immunodeficiency virus (HIV) protein fragments which have antiviral activity, and particularly relates to HIV peptides derived from the HIV transmembrane glycoprotein (gp41) which inhibit HIV-induced cell-cell fusion. This invention further relates to methods for the inhibition of enveloped viral infection, and to methods that modulate biochemical processes which involve coiled coil peptide interactions.
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Bolognesi Dani P.
Matthews Thomas J.
Wild Carl T.
Duke University
Gupta Anish
Schain Howard E.
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