Compounds which inhibit HIV replication

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...

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4352351, 435375, 530324, 514 12, C12N 508, A61K 3816

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active

056564805

ABSTRACT:
This invention relates to human immunodeficiency virus (HIV) protein fragments which have antiviral activity, and particularly relates to HIV peptides derived from the HIV transmembrane glycoprotein (gp41) which inhibit HIV-induced cell-cell fusion. This invention further relates to methods for the inhibition of enveloped viral infection, and to methods that modulate biochemical processes which involve coiled coil peptide interactions.

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