Compounds that stimulate glucose utilization and methods of use

Details Compounds that stimulate glucose utilization and methods of use Compounds that stimulate glucose utilization and methods of use

2006-07-11

2006-07-11

Davis, Zinna Northington (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

C514S529000, C560S123000, C560S124000

Reexamination Certificate

active

07074828

ABSTRACT:
The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells:wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, i and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.

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