Compounds that modulate processes associated with IgE...

Details Compounds that modulate processes associated with IgE... Compounds that modulate processes associated with IgE...

2002-03-15

2008-09-16

Pak, Michael (Department: 1646)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

Reexamination Certificate

active

07425418

ABSTRACT:
The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds that utilize a retinoid X receptor as a surrogate analyte and methods of using the compounds in a variety of in vitro, in vitro and ex vivo contexts.

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Egea, Pascal F., Crystal Structure of the Human RXRα Ligand-Binding Domain Bound to its Natural Ligand: 9-cis Retinoic Acid,EMBOJ2000; 19:2592-2601.
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