Compounds that inhibit (block) bitter taste in composition...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S378000

Reexamination Certificate

active

08076491

ABSTRACT:
The present invention relates to the discovery that specific human taste receptors in the T2R taste receptor family respond to particular bitter compounds present in, e.g., coffee. Also, the invention relates to the discovery of specific compounds and compositions containing that function as bitter taste blockers and the use thereof as bitter taste blockers or flavor modulators in, e.g., coffee and coffee flavored foods, beverages and medicaments. Also, the present invention relates to the discovery of a compound that antagonizes numerous different human T2Rs and the use thereof in assays and as a bitter taste blocker in compositions for ingestion by humans and animals.

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patent: 2006/0263411 (2006-11-01), Tachdjian et al.
patent: 2007/0037212 (2007-02-01), Li et al.
patent: 2009/0274632 (2009-11-01), Li et al.
Sabbioni et al., Chem. Res. Toxicol, (2000), vol. 13, pp. 82-89.
International Search Report on International Application No. PCT/US11/21302, mailed Jun. 16, 2011.

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