Compounds that bind P2Y 2 or P2Y 1 receptors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S023000, C514S025000, C514S053000, C514S274000, C514S311000, C514S422000, C514S425000, C514S529000, C514S547000, C514S562000, C514S572000, C514S574000

Reexamination Certificate

active

07056889

ABSTRACT:
The invention provides peptides and compounds that can bind to P2Y2receptors that are useful for modulating the secretion of mucus within mucosal surfaces.

REFERENCES:
patent: 5789391 (1998-08-01), Jacobus et al.
patent: 5837861 (1998-11-01), Pendergast et al.
patent: 5958897 (1999-09-01), Jacobus et al.
patent: 5972904 (1999-10-01), Jacobus et al.
patent: 5981506 (1999-11-01), Jacobus et al.
patent: 5985849 (1999-11-01), Kindon et al.
patent: 6107091 (2000-08-01), Cowsert
patent: 6107297 (2000-08-01), Kindon et al.
patent: 6200981 (2001-03-01), Kindon et al.
patent: 6264975 (2001-07-01), Boucher, Jr.
patent: 6277855 (2001-08-01), Yerxa
patent: 6331529 (2001-12-01), Yerxa et al.
patent: 6436910 (2002-08-01), Yerxa et al.
patent: 6444115 (2002-09-01), Hodges et al.
patent: 6462028 (2002-10-01), Pendergast et al.
patent: 6475360 (2002-11-01), Hodges et al.
patent: 2003/0129157 (2003-07-01), Sonneville-Aubrun et al.
patent: 2003/0176358 (2003-09-01), Egawa et al.
patent: 1 023 836 (2000-08-01), None
patent: WO 96/27370 (1996-09-01), None
Bouchie, Julie L., et al., “P2Y Receptor Regulation of PAI-1 Expression in Vascular Smooth Muscle Cells”,Arteriosclerosis, Thrombosis, and Vascular Biology, (Mar., 2000),866-873.
Garrad, Richard C., et al., “Structural Basis of Agonist-induced Desensitization and Sequestration of the P2Y2 Nucleotide Receptor”,The Journal of Biological Chemistry, 273 (45), (Nov., 1998),29437-29444.
Gorodeski, George I., “Expression, Regalation, and Function of P2X4 Purinergic Receptor in Human Cervical Epithelial Cells”,American Journal of Physiology-Cell Physiology, 282, (2002),C84-C93.
Gorodeski, George I., et al., “Regulation by Retinoids of P2Y2 Nucleotide Receptor mRNA in Human Uterine Cervical Cells”,American Journal of Physiology, 275, (1998), C758-C765.
Gorodeski, George I., et al., “Regulation of the Paracellular Permeability of Cultured Human Cervical Epithelium by a Nucleotide Receptor”,J. Soc. Gynecol. Invest, 2 (5), (Sep.-Oct., 1995),716-720.
Gorodeski, George I., “Regulation of Transcervical Permeability by Two Distinct P2 Purinergic Receptor Mechanisms”,American Journal of Physiology-Cell Physiology, 282, (2002),C75-C83.
Insel, Paul A., et al., “P2Y Receptors of MDCK Cells: Epithelial Cell Regulation by Extracellular Nucleotides”,Clinical and Experimental Pharmacology and Physiology, 28, (2001),351-354.
Jumblatt, James E., et al., “Regulation of Ocular Mucin Secretion by P2Y2 Nucleotide Receptors in Rabbit and Human Conjunctiva”,Experimental Eye Research, 67, (1998),341-346.
Santiago-Perez, Laura I., et al., “P2Y2 Nucleotide Receptor Signaling in Human Monocytic Cells: Activation, Desensitization, and Coupling ot Mitogen-Activated Protein Kinases”,Journal of Cellular Physiology, 187, (2001), 196-208.
Velazquez, Betty, et al., “Differential Agonist-induced Desensitization of P2Y2 Nucleotide Receptors by ATP and UTP”,Molecular and Cellular Biochemistry, 206, (2000),75-89.
Erb, L. , et al., “An RGD Sequence in the P2Y2 Receptor interacts with alpha-v-beta-3 Integrins and is Required for Go-Mediated Signal Transduction”,The Journal of Cell Biology, 153, (Apr. 30, 2001),491-501.
Insel, P. A., et al., “P2Y Receptors of MDCK Cells: Epithelial Cell Regulation by Extracellular Nucleotides”,Clinical and Experimental Pharmacology and Physiology, 28, (2001),351-354.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Compounds that bind P2Y 2 or P2Y 1 receptors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Compounds that bind P2Y 2 or P2Y 1 receptors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Compounds that bind P2Y 2 or P2Y 1 receptors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3689782

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.