Compounds of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime wh

Details Compounds of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime wh Compounds of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde oxime wh

1987-02-26

1993-06-15

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546335, 546338, A61K 3144, C07D21170

Patent

active

052198723

ABSTRACT:
Compounds useful in the treatment of Alzheimer's disease, senile dementia, or memory disorders which have the formula ##STR1## in which R represents a hydrogen atom, a linear, branched or cyclic alkyl radical, saturated or unsaturated, containing up to 8 carbon atoms, possibly substituted by a free or esterified carboxy radical or R represents an aralkyl radical containing up to 10 carbon atoms and R' represents a linear or branched, saturated or unsaturated, alkyl radical, containing up to 8 carbon atoms, a radical --COalk.sub.1 or a radical --(CH.sub.2).sub.2 N(alk.sub.2).sub.2, alk.sub.1 and alk.sub.2 representing an alkyl radical containing up to 8 carbon atoms, as well as their addition salts with acids. Also compositions containing the same, method of preparation and method of treatment using the same.

REFERENCES:
patent: 3004979 (1961-10-01), Druey et al.
patent: 4710508 (1987-12-01), Bergmeier et al.

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